Methotrexate 2.5mg
Methotrexate · tablet
Lowest price
$16.82
Save up to $8.25
Last verified:
Disease-modifying agent for rheumatoid arthritis, psoriasis, and certain cancers. Taken once weekly with folic acid supplementation.
Methotrexate 2.5mg is available at 9 pharmacy chains in Canada, with prices ranging from $16.82 to $25.07. You could save up to $8.25 by choosing Costco Pharmacy - Brandon over Guardian Pharmacy - Kerrisdale.
Prices across 9 pharmacy chainsSorted by price
Save up to $8.25 (33%)
by choosing Costco Pharmacy - Brandon over Guardian Pharmacy - Kerrisdale
Cheapest option breakdown
Why prices differ
What drives the $8.25 gap?
The dispensing fee is the biggest factor in the price difference for this medication. This is a flat fee pharmacists charge per fill — it can vary by over $7 between chains.
Price at each chain
Visual comparison — green bar = cheapest
Know a better price?
Help others save by submitting the price you paid.
Submit a PriceWhere to Buy Methotrexate 2.5mg
Methotrexate 2.5mg is available at 9 pharmacy chains across 42 cities
Methotrexate 2.5mg at Shoppers Drug Mart
Available in 24 locations · Shoppers Drug Mart is Canada's largest pharmacy chain
$23.34
View all pricesCostco Pharmacy - Brandon
Brandon, Kelowna, Peterborough +31 more
$16.82
CheapestWalmart Pharmacy - Polo Park
Winnipeg, Ottawa-Gatineau, Victoria +26 more
$22.32
London Drugs - Saguenay
Saguenay, Winnipeg, Toronto +18 more
$23.07
Medicine Shoppe - Brentwood
Calgary, Victoria, Edmonton +2 more
$23.10
Familiprix - Saint-Roch
Quebec City, Montreal
$23.17
Shoppers Drug Mart - Portage Place
Winnipeg, Montreal, Quebec City +21 more
$23.34
Rexall - Trois-Rivières
Trois-Rivières, Winnipeg, Montreal +22 more
$23.61
Jean Coutu - Mont-Royal
Montreal, Quebec City
$23.69
Guardian Pharmacy - Kerrisdale
Vancouver, Victoria, Toronto +4 more
$25.07
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Head-to-head comparisons
Frequently Asked Questions
Common questions about Methotrexate 2.5mg pricing and availability
How much does Methotrexate 2.5mg cost without insurance?
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Methotrexate 2.5mg tablet costs as low as $16.82 at Costco Pharmacy - Brandon, and up to $25.07 at Guardian Pharmacy - Kerrisdale. Prices vary by pharmacy chain and location in Canada. We compare prices at 9 pharmacy chains to help you find the lowest price.
Where can I buy Methotrexate in Canada?
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Methotrexate 2.5mg is available at 9 pharmacy chains across 8 cities in Canada, including Brandon, Winnipeg, Saguenay, Calgary, Quebec City and more. The cheapest option is Costco Pharmacy - Brandon at $16.82.
How much does Methotrexate cost at Shoppers Drug Mart?
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Methotrexate 2.5mg costs $23.34 at Shoppers Drug Mart in Winnipeg. This includes the dispensing fee of $9.28. You could save $6.52 by switching to Costco Pharmacy - Brandon.
Do I need a prescription for Methotrexate?
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Yes, Methotrexate 2.5mg requires a valid prescription from a licensed healthcare provider in Canada. Visit your doctor or use a telemedicine service to get a prescription, then compare pharmacy prices on TransparentMedz to find the lowest cost.
How can I save money on Methotrexate?
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You can save up to $8.25 (33%) on Methotrexate 2.5mg by choosing Costco Pharmacy - Brandon over Guardian Pharmacy - Kerrisdale. Other ways to save include: asking for generic alternatives, checking if your insurance covers it, using pharmacy loyalty programs, and buying in larger quantities to reduce per-unit costs.
Canadian Health Resources
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Health Canada Drug Product Database
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Ontario Drug Benefit Formulary
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Canadian Pharmacists Association
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BC PharmaCare
British Columbia drug coverage and formulary
RAMQ (Quebec)
Quebec prescription drug insurance plan