Methotrexate · tablet
Lowest price
$16.82
Save up to $8.25
Last verified:
Disease-modifying agent for rheumatoid arthritis, psoriasis, and certain cancers. Taken once weekly with folic acid supplementation.
Methotrexate 2.5mg is available at 9 pharmacy chains in Canada, with prices ranging from $16.82 to $25.07. You could save up to $8.25 by choosing Costco Pharmacy - Brandon over Guardian Pharmacy - Kerrisdale.
Save up to $8.25 (33%)
by choosing Costco Pharmacy - Brandon over Guardian Pharmacy - Kerrisdale
What drives the $8.25 gap?
The dispensing fee is the biggest factor in the price difference for this medication. This is a flat fee pharmacists charge per fill — it can vary by over $7 between chains.
Visual comparison — green bar = cheapest
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Submit a PriceMethotrexate 2.5mg is available at 9 pharmacy chains across 42 cities
Available in 24 locations · Shoppers Drug Mart is Canada's largest pharmacy chain
$23.34
View all pricesCostco Pharmacy - Brandon
Brandon, Kelowna, Peterborough +31 more
$16.82
CheapestWalmart Pharmacy - Polo Park
Winnipeg, Ottawa-Gatineau, Victoria +26 more
$22.32
London Drugs - Saguenay
Saguenay, Winnipeg, Toronto +18 more
$23.07
Medicine Shoppe - Brentwood
Calgary, Victoria, Edmonton +2 more
$23.10
Familiprix - Saint-Roch
Quebec City, Montreal
$23.17
Shoppers Drug Mart - Portage Place
Winnipeg, Montreal, Quebec City +21 more
$23.34
Rexall - Trois-Rivières
Trois-Rivières, Winnipeg, Montreal +22 more
$23.61
Jean Coutu - Mont-Royal
Montreal, Quebec City
$23.69
Guardian Pharmacy - Kerrisdale
Vancouver, Victoria, Toronto +4 more
$25.07
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Head-to-head comparisons
Common questions about Methotrexate 2.5mg pricing and availability
Methotrexate 2.5mg tablet costs as low as $16.82 at Costco Pharmacy - Brandon, and up to $25.07 at Guardian Pharmacy - Kerrisdale. Prices vary by pharmacy chain and location in Canada. We compare prices at 9 pharmacy chains to help you find the lowest price.
Methotrexate 2.5mg is available at 9 pharmacy chains across 8 cities in Canada, including Brandon, Winnipeg, Saguenay, Calgary, Quebec City and more. The cheapest option is Costco Pharmacy - Brandon at $16.82.
Methotrexate 2.5mg costs $23.34 at Shoppers Drug Mart in Winnipeg. This includes the dispensing fee of $9.28. You could save $6.52 by switching to Costco Pharmacy - Brandon.
Yes, Methotrexate 2.5mg requires a valid prescription from a licensed healthcare provider in Canada. Visit your doctor or use a telemedicine service to get a prescription, then compare pharmacy prices on TransparentMedz to find the lowest cost.
You can save up to $8.25 (33%) on Methotrexate 2.5mg by choosing Costco Pharmacy - Brandon over Guardian Pharmacy - Kerrisdale. Other ways to save include: asking for generic alternatives, checking if your insurance covers it, using pharmacy loyalty programs, and buying in larger quantities to reduce per-unit costs.
Official resources for drug information, coverage, and patient assistance
Health Canada Drug Product Database
Official Canadian drug database with DIN lookup
Ontario Drug Benefit Formulary
Check if your drug is covered by Ontario public plans
Canadian Pharmacists Association
Find a licensed pharmacist or pharmacy near you
BC PharmaCare
British Columbia drug coverage and formulary
RAMQ (Quebec)
Quebec prescription drug insurance plan